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HOW DO hGH THERAPIES MEASURE UP ?

"I don't want to achieve immortality through my work; I want to achieve immortality through not dying."
- Woody Allen                    

 

CHAPTER 8

We have reviewed the studies on hGH injections and provided the details of a variety of ways to increase your own GH secretion through diet, exercise, and the proper natural secretagogues. Now, the ultimate question in evaluating the differences among these various modes of GH therapy becomes, "Which GH therapy is right for me?"

Here are some areas of comparison to consider in answering this question:

        SYMBIOTROPIN       GH INJECTIONS
   Dosage Form       Drink       Injection
   Side Effects       Rare *       Several **
   Cost per month       $120 - $200       $800 - $2,000
   Effectiveness       Within 30 days       60 days +
   Availability       Readily       Restricted
   Convenience       Easy to travel with       Must be refrigerated
   Allergies       Rare       Somewhat common
   Biocompatability       Natural       Synthetic
   Support of IGF-1 formation       Yes       No
   Contraindications       Rare       A few ***

* The only side effect observed with Symbiotropin was a mild allergic reaction (skin rash) to citric acid.
** Side effects of GH injections include musculoskelatal pain and edema.
*** Contraindicated in cancer patients and those with existing edema (swelling) of unknown case.

The top priority in replacing hormones should be to do it as naturally as possible. With this as a primary objective, growth hormone replacement is ideal because, unlike other hormones, it continues to be produced in significant amounts right into old age. So rather than replacing GH, our primary focus is on stimulating its release. The diet and exercise recommendations that we have outlined for promoting GH release are just as important in preventing symptoms of aging as they are in treating them. We have repeatedly observed patients who are able to maintain youthful IGF-1 levels well into their 70's just by maintaining a consistent adherence to a GH promoting lifestyle. But this is not the case for everyone.


Many factors affect the ability of the body to release
growth hormone and form IGF-1, including:

Physical and Emotional stress Chronic disease Liver dysfunction Pancreatic dysfunction Poor diet Genetic predispostion

In addition, by the time many people consider themselves to be candidates for growth hormone therapy, they have reached a point of depletion that they are not able to tolerate the intensity of a GH promoting exercise program.
This can often be overcome by kick-starting the body with Symbiotropin or injections.

 

Step 1: Measure your IGF-1 levels.

IGF-1 levels are relatively stable, so you do not need to be concerned about what time of day or month to measure them. Remember, when we talk about the importance of growth hormone therapy, we are referring to restoring IGF-1 to youthful levels. Before using any GH therapy, aside from diet and exercise, a deficiency must be established. A general consensus exists among scientists and physicians that any person regardless of age, whose IGF-1 levels are found to be below 100ng/ml, is considered to be GH deficient. However, the caveat is that the normal IGF-1 level does not exclude the diagnosis of growth hormone deficiency. This is the case for about 80% of people over the age of 40 years old. From clinical experience, deficiency is often found in younger patients with hysterectomy, chronic fatigue syndrome, difficulty in weight control, chronic diseases, and HIV. The existence of any of these conditions warrants the measurement of IGF-1 levels.

In establishing an IGF-1 deficiency, a first course of action may include Symbiotropin in combination with diet and exercise therapy. The standard recommendation. is two tablets/day in five days on and two days off intervals for three months, then repeat the cycle if necessary. This protocol may be varied according to test results and symptomatic changes, as follows:

If IGF-1 Levels Are (in ng/dl):

Below 100: Use double dose of Symbiotropin (morning and night) until levels reach 200, or until symptoms stabilize.
                   Then continue with single dose (2 tablets/day) as maintenance.

100-200: Follow standard dosing. If symptomatic improvement is not progressing as expected, double dose for 1-2
              weeks, then maintain at single dose (2 tablets/day).

200-350: Follow standard dosing, be sure to re-check levels after each 3-month cycle to evaluate the next stage of
              your protocol.

350+: Generally, this does not represent a deficiency. It is recommended to follow dietary and exercise
          recommendations to -maintain these levels. The exceptions are:

  • If you have reached these levels with the use of Symbiotropin, you will probably need to maintain this ideal level with continued single dosing at three month on and one month off intervals. Keep re-testing every 3-4 months.

  • If your initial IGF-1 levels appear normal, but you are exhibiting other symptoms of GH deficiency-you may not be responding adequately to your circulating IGF-1. Follow one half or single dosing of Symbiotropin for a threemonth cycle. then evaluate symptomatic improvement in order to determine continuing use.

 

Step 2: Evaluate your lifestyle.

No matter what your IGF-1 levels are, the lifestyle that you choose will make all the difference in maintaining and increasing your IGF-1. Whether you are using injections or Symbiotropin, your diet and exercise habits will potentiate your response.

  • Are you currently exercising 4 days/week or more?

  • In your current state of health, are you able to begin a GH promoting exercise program?

  • Does your diet supplement program resemble the one that is suggested for promotion of GH?

  • Are you willing to make changes in your diet in order to more effectively promote GH secretion?

If your answer to the second question is no, keep asking yourself this key question throughout the term of your growth hormone therapy - you may be surprised at how quickly the answer will become, "Yes!"

 

Step 3: Evaluate your symptoms.

As scientists, we are familiar with the importance of blood tests in measuring response, but the most important thing to monitor is symptomatic improvement. After all, what difference does any therapy make if the patient doesn't feel better ? The patient self-assessment that is provided in the following chapter is an essential part of growth hormone therapy.
It is important for you and your physician to monitor the rate of change in various areas in order to determine an
ongoing treatment protocol.

_______________________________

I am sleeping much better at night. Blood pressure is normal after being borderline high for several years.

-JH. (Male, Age 65)

_______________________________

 

 

Back to Chapter 7                                                                              Chapter 9 ►                             


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